Pharmaceutical substances (APIs)

Continuous process replaces batch operation

Continuous production of active pharmaceutical ingredients

Whether you are producing antivirals, anti-asthmatic drugs, hormone derivatives, orlistats or statins: In the production of active pharmaceutical ingredients (API), rotary pressure filters (type RPF) and indexing belt filters (type BF) are particularly suitable for solid-liquid separation. These filter systems enable continuous processes that demonstrate vast potential for increasing yields and improving quality assurance. At the same time, our filters meet the highest demands as regards product quality, purity and process reliability.

Benefits at a glance:

  • Continuous production and monitoring
  • Various options for cake treatment
  • From tiny batches to mass production
  • Top process reliability and end product quality
  • Validation conformity

Closed filtration systems

Rotary pressure filters and indexing belt filters are closed and inert systems that are successfully used by the pharmaceutical industry in both continuous and batch production. The solutions help manufacturers ensure absolute purity and high product quality. BHS also offers both systems to customers and interested parties as laboratory and pilot filters for product and process development. These models provide reliably reproducible results and enable the production of very small quantities.

Pressure or vacuum

With the rotary pressure filter, all process steps take place in discrete, pressure-tight segment zones. Single-batch production in pharmaceutical quality is made possible by supporting counter-current washing, displacement washing and closed-cycle washing. The indexing belt filter is a vacuum filter that makes it possible to separate sedimentation solids gently and reliably. The filter cake formed on the conveyor belt can be further processed in various ways.

Continuous processes

BHS-X20_062_F_S_C.psd
Rotary pressure filter of type RPF X20 with TwinDrive and an active filter area of 8.6m²

Continuous processes

In the pharmaceutical industry, continuous production is increasingly replacing production based on the batch principle. Solid-liquid separation based on efficient, continuous filtration solutions is the key to achieving this. The rotary pressure filter is a true success story in this field of application. It significantly boosts productivity in the manufacture of antibiotics.

International standards

BHS-BF100-050_031-Schatten.psd
Indexing belt filter of type BF 100-050 in pharmaceutical design. The pharmaceutical version is certified according to EN ISO 22716 and has ground and polished surfaces

International standards

When it comes to the use of our products in the pharmaceutical industry, we naturally consider the standards and specifications according to GMP, CIP and ATEX. All systems can be validated and are manufactured in compliance with highly demanding quality guidelines. They address applications such as manufacturing intermediates or producing active substances.

Our filters in use

Indexing belt filter (BF)

This type of vacuum filter is particularly gentle on sediments.

Rotary pressure filter (RPF)

A single rotation of the drum entails a number of different process steps, demonstrating the many facets of filtration.

Tests give certainty

Which technology is the right one for your process? Don’t leave anything to chance. Based on your specifications, we carry out testing and identify the best solution for you in our filtration laboratory.

Success stories

Events

ACHEMA 2021

14.06.-18.06.2021 | Frankfurt am Main (Germany)
Hall 5, Booth C34

Satisfied customers worldwide

Contact

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Find your personal contact person on site. We are there for you worldwide.